Sports & Athletes

Greatest Upsets in March Madness Tournament History

A curated compilation of the most shocking and historic upsets in NCAA Division I men's basketball tournament history, highlighting lower-seeded teams that defeated heavy favorites and altered the course of the tournament.

ID: 43325
Items: 20
Total Votes: 0
Forks: 0
Disclosure: Some links are affiliate links. If you buy through them, we may earn a commission at no extra cost to you, supporting our work without affecting our ratings.
Want to feature your product on this list?
Sponsorship

Get targeted exposure with custom position pinning and highlighted placement.

Contact Us
1
0

Lehigh vs. Villanova (2012)

Visit

The highest seed ever defeated by the lowest seed in tournament history. Lehigh, a 16-seed, upset Villanova, an 1-seed, with a score of 74-54, breaking a decades-long streak of perfect records for number one seeds.

2
0

Seward vs. Duke (2023)

Visit

An 11-seed from the MEAC delivered one of the most improbable victories in recent memory by defeating the 6-seed Duke Blue Devils. Seward’s balanced attack and defensive intensity completely neutralized Duke’s star power.

3
0

UMBC vs. Virginia (2018)

Visit

The first 16-seed to ever defeat a 1-seed in men’s basketball history. UMBC’s aggressive three-point shooting and stifling defense led to a historic 74-54 victory over the national champion Cavaliers, ending their perfect run.

4
0

Holy Cross vs. Duke (2005)

Visit

A 12-seed from the Patriot League stunned the college basketball world by defeating the 5-seed Blue Devils. Holy Cross’s disciplined defense and efficient offense disrupted Duke’s flow in a memorable first-round game.

5
0

Iowa State vs. Syracuse (2005)

Visit

The 8-seed Cyclones utilized a swarming full-court press to break down the 1-seed Orange in overtime. This victory showcased the power of defensive intensity and clutch shooting against a seasoned, high-profile opponent.

6
0

George Mason vs. UConn (2006)

Visit

The 11-seed Patriots made a Cinderella run to the Final Four, beating the 3-seed Huskies en route. Their disciplined team play and veteran leadership allowed them to overcome a talented UConn squad in the second round.

7
0

VMI vs. Duke (2003)

Visit

The 16-seed Keydets played a near-flawless defensive game against the 1-seed Blue Devils, keeping the score close until the final moments. Although Duke eventually won, VMI’s performance is remembered as a legendary upset attempt.

8
0

Richmond vs. Duke (1998)

Visit

The 9-seed Spiders delivered a masterclass in defensive pressure, forcing turnovers and limiting Duke’s shooting efficiency. Their gritty performance in the first round remains one of the most celebrated upsets of the late 90s.

9
0

LSU vs. Connecticut (2006)

Visit

The 12-seed Tigers shocked the 5-seed Huskies with a dominant offensive performance and rebounding advantage. LSU’s depth and physicality overwhelmed Connecticut, securing a memorable victory in the second round.

10
0

Iowa vs. Purdue (2005)

Visit

While not a traditional seed-based upset, this regional final saw the 3-seed Hawkeyes defeat the 1-seed Boilermakers in a thrilling contest. Iowa’s defensive prowess and clutch free-throw shooting sealed the historic win.

11
0

Florida Gulf Coast vs. Duke (2013)

Visit

The 15-seed Eagles captured national attention with their high-octane offense and energetic style of play. Although they narrowly lost to Duke, their spirited performance against a top-tier team defined the 'Dunk City' era.

12
0

Northwestern vs. Michigan State (2012)

Visit

The 12-seed Wildcats utilized a strong interior presence and disciplined offense to upset the 5-seed Spartans. Northwestern’s veteran leadership and steady play disrupted Michigan State’s rhythm in a crucial first-round matchup.

13
0

St. Bonaventure vs. Michigan (2006)

Visit

The 11-seed Bonnies played exceptional team basketball, sharing the ball effectively to overcome the 6-seed Wolverines. Their unselfish play and defensive discipline resulted in a stunning victory that highlighted the tournament's unpredictability.

14
0

VCU vs. Georgetown (2012)

Visit

The 11-seed Rams employed an aggressive full-court press that disrupted Georgetown’s offense throughout the game. VCU’s relentless energy and efficient scoring in the second half led to a decisive upset over the 6-seed Hoyas.

15
0

Arizona vs. Kentucky (1998)

Visit

The 2-seed Wildcats lost to the 7-seed Wildcats in a shocking regional final, highlighting the tournament's volatility. Arizona’s balanced attack and key baskets in the final minutes secured a memorable upset over the defending champs.

16
0

Oklahoma State vs. Arizona (2013)

Visit

The 11-seed Cowboys defeated the 6-seed Wildcats in a tightly contested first-round game. Oklahoma State’s strong defensive effort and timely three-point shooting neutralized Arizona’s offensive capabilities for a crucial victory.

17
0

Missouri vs. North Carolina (2012)

Visit

The 7-seed Tigers upset the 2-seed Tar Heels in a hard-fought battle that showcased Missouri’s depth. The Tigers’ ability to control the tempo and limit UNC’s transition game resulted in a significant first-round win.

18
0

Wichita State vs. Kentucky (2013)

Visit

The 9-seed Shockers played a disciplined defensive game against the 1-seed Wildcats, keeping the score close for much of the contest. Though Kentucky won, Wichita State’s performance was widely regarded as one of the best efforts by a lower seed.

19
0

Texas Southern vs. Ohio State (2015)

Visit

The 15-seed Tigers challenged the 2-seed Buckeyes with a high-powered offense that kept the game competitive. Texas Southern’s aggressive play and scoring bursts made it one of the closest 15-vs-2 games in tournament history.

20
0

Cal State Northridge vs. North Carolina (2015)

Visit

The 15-seed Matadors pushed the 2-seed Tar Heels to the limit with a spirited defensive effort and efficient shooting. Although NC State won narrowly, CSUN’s performance highlighted the potential for lower seeds to compete with blue-blood programs.