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您能否展望这种肾素抑制剂的未来应用前景?Would you like to outlook the direct rennin inhibition in the future?
肾组织肾素活性在3个观察组间差异无显著性。The renal rennin activity showed no significant difference among 3 groups.
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嗯,肾素抑制剂确实是一种新药,一种很有前景的药物。Well, no question that rennin inhibitors are a new class of agents, promising agents.
用药前后肾小球滤过率和肾素活性均无显著性差异。No significant changes were observed in glomerular filtration rate and rennin activity after administration of RDA.
如果这一点得到证实的话,那么我们就会更有理由在单独用药和联合治疗中使用肾素抑制剂了。If these would demonstrate that then there would be an even stronger rationale to use rennin inhibitors alone or in combination.
丙泊酚抑制肾素血管紧张素系统可能是其对血液动力学抑制的机制之一。Propofol can inhibit rennin angiotensin system, which may be one of the mechanisms responsible for hemodynamic depression of propofol.
此外,本发明还公开了检测人肾素结合蛋白基因SNP位点的方法及其检测引物。Moreover, the invention also discloses a method for detecting the SNP locus of the human rennin binding protein gene and a detection primer.
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肾素血管紧张素系统在调节血压和水、盐代谢中发挥着重要作用。The rennin angiotensin system had been recognized for many years as a key regular of systemic blood pressure and the metabolism of water and salt.
本发明涉及一种含有肾素抑制剂与叶酸类化合物的药物组合物及其用途,属于药学领域。The invention relates to a pharmaceutical composition containing a rennin inhibitor and a folic acid compound and an application thereof, which belong to the field of pharmacology.
之所以说这种新药很有前景还有一部分原因是,我们已经开始懂得肾素对血管紧张素II的形成有一定的作用,且这种作用不依赖于传统的作用途径。The promise of these drugs is also connected to the fact that we have begun to understand that rennin may have effects independently on the formation of angiotensin II to the traditional pathways.