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提供了调节大麻素受体的杂环化合物。Heterocyclic compounds which modulate cannabinoid receptors are presented.
事实上当发生肝纤维化时肝脏存在大麻素受体。It turns out that there actually cannabinoid receptors in the liver once you have fibrosis.
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因此在发生纤维化的肝脏大麻素受体既有抗纤维化作用也有促纤维化作用。So in fibrotic livers you can find cannabinoid receptors that have both anti- and pro-fibrogenic effects.
这三个药物都作用于大脑中的大麻素受体,其也是大麻的作用靶点。All three of the drugs work on the cannabinoid receptors in the brain, which are also targeted by marijuana.
原来这是因为我们舌头上甜味的受体与大麻素的受体处于同种细胞里。It turns out that sweetness receptors are present in the same cells as cannabinoid receptors on our tongues.
我们也了解到人的身体里有一个大麻成分受体的网络,能够调整痛感,食欲和短期记忆。And we learn that the body contains a network of cannabinoid receptors that modulate pain, appetite and short-term memory.
目的研究外周内源性大麻受体激动剂及其受体2亚型在搔痒中的作用。Objective To evaluate the role of peripheral cannabinoid receptor 2 and endogenous agonists in the modulation of pruritus.
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小鼠变老时,大麻素受体与某特定蛋白质的结合变差,似乎会让动物比较不嗜酒。As the mice age, the cannabinoid receptor binds less frequently to a specific protein, which seems to diminish the animals' taste for alcohol.
在这次新研究中,研究者们测试了大麻中五种化学成分对超级细菌MRSA,即甲氧西林耐药金黄色葡萄球菌的抑制作用。In the new study researchers tested five cannabinoid marijuana ingredients against the superbug MRSA, methicillin-resistant Staphylococcus aureus.
目的探讨大麻素受体激动剂WIN55212-2对体外大鼠心肌缺血再灌注损伤的保护作用。Objective To explore the protective effects of WIN55212-2, an agonist of cannabinoid receptor, on ischemia-reperfusion injury in isolated rat hearts.
美国目前只有12州将合成大麻列为禁药,海军官校所在的马里兰州虽未禁止,但军方已明令含军校生在内的军人不得吸食。Only 12 U. S. states as the synthetic cannabinoid drugs, the Naval Academy, Maryland, where although not prohibited, but the military has explicitly with the military cadets, including not smoking.