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上述正常红细胞浓度使得红血球生成几乎完全停止。The above-normal red cell concentration produces an almost complete cessation of erythropoiesis.
高通量透析器较普通低通量透析器能更有效清除红细胞生成抑制因子。High-flux dialyzer are more effective in clearing the erythropoiesis inhibitors than low-flux dialyzer.
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结果提示,白血病细胞相关抑制物对正常红细胞系造血也有抑制作用。The result indicates that leukemic cell-associated inhibitor also has inhibitory activity on normal erythropoiesis.
结论尿毒症患者血清中存在红细胞生成抑制因子,其对红系造血祖细胞的抑制作用具有剂量依赖性。Conclusion The erythropoiesis inhibitors might exist in uremia sera which had a dose-dependent inhibitory effects on CFU-E and BFU-E proliferations.
铁是血红蛋白合成的一种重要物质,人体铁的丢失主要来自人的正常吸收及红细胞生成的刺激。Iron is important for the formation of haemoglobin and its loss from the body is normally followed by increased absorption and stimulation of erythropoiesis.
红细胞发生的研究主要依赖于MEL细胞系和分离到的少量的小鼠成红细胞。Most studies of erythropoiesis have been performed either with the virally transformed MEL cells or with the scarce erythroblasts within unhomogeneous cell populations.
结论尿毒症患者血清抑制小鼠骨髓红系祖细胞集落形成,随患者血清浓度的增加,抑制作用增强,具有剂量依赖性。Conclusion The erythropoiesis inhibitors exist in uremic sera which has a dose-dependent inhibitive effects on the growth CFU-E and BFU-E of normal mice bone marrow cells.
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膳食摄入,促红细胞生成素使用,透析膜的选择,透析是否充分等均影响患者的营养情况。The intake from diets, application of erythropoiesis stimulating factor, the selection of dialytic membrane and the adequate dialysis all rendered influence on their nutrition.
我们研究了维太明、EDTA和铅在孕期和哺乳期对铅暴露胎鼠和幼鼠生长发育、原卟啉和血压的影响。We studied the effects of VITALCARE, EDTA and lead exposure on lead toxicity, fetal and neonatal growth, erythropoiesis and blood pressure during pregnancy and lactation in rats.
结果表明,切除内脏大神经大鼠低氧时的红细胞参数改变与单纯低氧对照比较,无显著性差异。The results suggested that the erythropoiesis in rats having bilateral splanchnic neurectomy was not significantly different from in intact rats when subjected to hypoxic hypoxia.