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已知SCF具有刺激黑色素干细胞的迁徙与黑色素生成。SCF has been suggested play an important role in melanocyte migration, survival and melanogenesis.
酪氨酸酶是黑色素合成中的关键酶,酪氨酸酶基因的突变将导致白化病。Tyrosinase is the essential enzyme in melanogenesis . The mutation of tyrosinase gene causes albinism.
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目的观察止血环酸抑制黑素瘤细胞的黑素合成作用并探讨其机理。Objective To observe the effect of acidum tranexamicum on melanogenesis of B16 melanoma cells and mechanism.
有关黑素原机理的最近理论和防止色素沉着的各种研究的评述。Recent theories on the mechanism of melanogenesis and the various approaches of depigmentation were reviewed.
紫外光亦可透过角质细胞的参与,藉由旁分泌调节,而影响黑色素生成。UV radiation also influences melanogenesis through a paracrine regulation process involving the keratinocytes.
结论两种化合物均显示有抑制黑素生成的作用,存在一定细胞毒性。Conclusion Arbutin and glabridin can inhibit melanogenesis in B16 murine melanoma cells, but there were some cell toxicity.
结论该方能抑制黑素细胞黑素合成,这可能是其治疗黄褐斑的作用机制之一。ConclusionThe recipe is effective in the treatment of chloasma by inhibiting the melanogenesis of A375 human melanoma cell.
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结论补骨脂含药血清有促进A375黑素瘤细胞增殖作用,并使A375人黑素瘤细胞合成黑素增加。Conclusion Serum containing Psoralea has strong effect of promoting A375 human melanoma cells proliferation and melanogenesis in vitro.
本文介绍了用曲酸、曲酸衍生物与有机酸配合制成抑制皮肤黑色素生成的新组分。The new compositions of inhibiting melanogenesis of skin formulated by kojic acid and its derivatives with organic acid are introduced in this paper.
观察中药黄芩对B16F小鼠黑素瘤细胞增殖、黑素含量、酪氨酸酶活性的影响。To study the regulation of proliferation, melanogenesis and tyrosinase activity in the responese of B16F murine melanoma cells to Radix Scutellariae.
目的探讨含补骨脂大鼠血清对A375细胞增殖及合成黑素功能的影响。Objective To study the effects of serum containing Psoralea on proliferation and melanogenesis in A375 human melanoma cells by serum pharmacological method.
另外,此三者之水煎剂对于黑色素之生成皆无显著影响,而黄芩水解物反而促进黑色素之生成,芍药水解物则具抑制作用。However, all of these three decoctions had no effect on melanin formation. The hydrolysate of PLR inhibited melanogenesis whereas the hydrolysate of SR promoted it.
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研究了烟酰胺对酪氨酸酶活性、人皮黑素细胞的增殖率、细胞周期动力学和黑素合成的影响。The impact of nicotinamide on the activity of tyrosinase, as well as the impact on the proliferation rate of human melanocytes, cell cycle kinetics and melanogenesis were studied.