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哈哈,还有一对乌头放到鸟笼里。Haha, there are a pair of aconitine into the cage.
而临床治疗上尚无特效解毒药治疗乌头碱中毒。But there is no effective medicine treat the aconitine poisoning.
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目的鉴定乌头碱在家兔尿中主要代谢产物。AIM To identify the main metabolites of aconitine in the urine of rabbits.
这周鸽市人很热闹,鸽子也不少,我还买了一只乌头。Pigeon City this week, people are busy, too many pigeons, I also bought a aconitine.
目的研究乌头碱对乳鼠心肌细胞的毒性作用。OBJECTIVE To investigate the toxicity effects of aconitine on neonatal rat cardiomyocytes.
目的探讨乌头碱中毒致心律失常的表现和对内皮功能的影响。Objective To explore clinical arrhythmia feature and the change of endothelium function in aconitine poisoning.
结论该方法所用试剂成本低、毒性小,适用于制备乌头碱、中乌头碱、次乌头碱对照品。Conclusion This method was at low cost, harmless and suitable for preparing mesaconitine, aconitine and hypaconitine.
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目的探讨乌头碱直流电离子导入对大鼠关节炎的镇痛机制。Objective To study the mechanism of analgesic effects of the iontophoresis of aconitine on the rat with adjuvant arthritis.
本法快速简便,准确灵敏,可作为双酯型乌头碱的含量测定方法。This method is quick and simple, accurate and sensitive, and available as a determination method for di-ester type of aconitine.
以乌头碱诱发大鼠心律失常,测定大鼠血浆内ET、NO、NOS、SOD,观察复方青山健心片对心肌细胞的保护作用。Use aconitine to induce arrhythmia, test ET, NO, NOS, SOD of rats" plasma, and observe the protective effects on cardiac myocytes."
方法中所用试剂成本低、毒性小,适用于乌头碱、中乌头碱、次乌头碱的提取分离以及对照品的制备。This method was at low cost, harmless and suitable for extracting, separating and preparing mesaconitine, aconitine and hypaconitine.
采用乌头碱和人肠内细菌体外温孵的方法,探讨乌头碱在肠内的生物转化规律。To study the biotransformation of 16-O-demethylaconitine in human intestine, aconitine was incubated with human intestinal bacteria in vitro.
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乌头碱中毒损害的靶器官主要为心血管系统,引起的严重的心律失常是致死的主要原因,主要表现为不同形式的心律失常。Cardiovascular system that is the main target organ damaged by Aconitine poisoning. which cause serious arrhythmia is the main reason of death.
因此培养患者有毒中药用药量、防中毒意识和改善产地用药习惯是从根本上预防和减少乌头类生物碱中毒的关键。Therefore, to culture toxic dosage-awareness and drug habit in patients is the key to prevent and reduce the rate of aconitine alkaloids poisoning.
药理试验结果表明,其中化合物1、5、7、8、14、15、17等均能对抗乌头碱引起的实验性心律失常,其中化合物14、15、17疗效显著。Pharmacological results showed that compounds 1, 5, 7, 8, 14, 15, 17 exhibited protective effects against experimental arrhythmias induced by aconitine.
在前期工作中,通过大量动物实验和临床治疗观察,结果显示双黄连治疗乌头碱中毒疗效显著。In early work, through a large number of animal experiments and clinical observation showed that Shuanghuanglian treat aconitine poisoning have significantly effect.
体外转染膀胱癌BIU-87细胞后,利用赤潮毒素作用后细胞表达绿色荧光蛋白的变化来检测赤潮毒素,初步建立一种以细胞为基础受体水平的赤潮毒素检测方法。Second, based on the changes of the expression of GFP in the BIU-87 cell which induced by the aconitine and HAB toxins, the concentration of the HAB toxins could be detected.
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合成了五组B环具不同取代基的黄酮和黄烷酮-7-o-异丙醇胺衍生物,并进行了对乌头碱诱发大鼠室性心律失常预防作用的药理试验。Five groups of B-ring substituted flavone and flavanone-7-O-isopropanolamine derivatives were synthesized and tested on rats for the ventricular arrhythmia induced by aconitine.
目的分析54例急性乌头碱中毒病例的临床和心电图资料,探讨其临床特征和心电图表现。Objective To analyze the clinical and electrocardiogram data of 54 cases of acute aconitine poisoning and to investigate the clinical characteristic and electrocardiogram manifestations.
本文报告了乌头碱及其类似物的毒性和对心脏收缩功能的影响,以及这二者与结构之间的关系。The present paper reports on the toxicity of aconitine and its nine selected analogs, their cardiac contractive function, and their structure-toxicity and structure-activity relationships.