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普遍的观点认为血流动力学因素在其中起着重要作用。Hemodynamic factors have been suggested to be important in atherogenesis.
因此,我们现在将注意力放在当代的动脉粥样化形成理论上。Thus we now turn our attention to contemporary theories of atherogenesis.
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氧化应激在致动脉粥样硬化中的基因表达调节中起关键作用。Oxidative stress plays a key role in regulation of gene expression during atherogenesis.
本研究旨在探讨CD40在动脉粥样硬化生成中的作用。The present study aimed to characterize the contribution of CD40 signaling to atherogenesis.
目的探讨血清胆红素水平与冠状动脉狭窄病变程度及血脂的关系。Objective To explore the relationship between serum bilirubin level and severity of coronary atherogenesis and serum lipid.
尽管由实验模型得到的数据支持CRP在动脉粥样硬化形成中的作用,但它的直接关系仍在讨论中。Although some data from experimental models support a role of CRP in atherogenesis , its direct inolement remains in question.
这表明黑米皮的抗动脉粥样硬化作用可能与其降低抗氧化型低密度脂蛋白抗体水平有关。Conclusion BRF has dramatically reduced serum anti ox LDL antibody levels and this effect may be related to its anti atherogenesis.
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越来越多的证据提示在从病损形成到斑块破裂的整个动脉粥样硬化形成过程中免疫系统起了非常关键的作用。Growing evidence suggests that the immune system plays a critical role in all the stages of atherogenesis , from lesion formation to plaque rupture.
本研究我们观察了在载脂蛋白E缺失小鼠中,血管周围肥大细胞对于动脉粥样硬化形成以及斑块稳定性的影响。In the present study, we investigated the contribution of perivascular mast cells to atherogenesis and plaque stability in apolipoprotein E–deficient mice.
成熟的树突状细胞把抗原提呈给T细胞并激活T细胞释放细胞因子参与动脉粥样硬化。Mature dendritic cells are capable of presenting antigen to T cells and activation of T cells leading to release of cytokines, which contribute to atherogenesis.
本课题拟通过动物实验研究番茄红素预防高同型半胱氨酸血症致动脉粥样硬化的作用和机制。To investigate the preventive effects and its mechanisms of lycopene supplementation for 12 wk on vascular atherogenesis induced by hyperhomocysteninemia in rats.
糖尿病的心血管并发症严重威胁着糖尿病患者的生命,其脂肪代谢紊乱可能在动脉粥样硬化的发生、发展中起了重要作用。Cardiovascular complication is threatening the lifes of diabetics. The lipid metabolic disorder played an important role in the genesis and development of atherogenesis.
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近年来,心血管疾病成为类风湿性关节炎患者主要死因,本文就类风湿性关节炎及其相关的动脉粥样硬化发生机制做一综述。In recent years, cardiovascular mortality became one of the leading causes of death in RA patients. The mechanisms of atherogenesis in RA patients are overview in this review.
我们假设PARP可能在动脉粥样硬化形成中起重要作用,它的抑制可能会减弱动脉粥样硬化实验模型中动脉硬化斑块的进展。We hypothesized that PARP may play an important role in atherogenesis and that its inhibition may attenuate atherosclerotic plaque development in an experimental model of atherosclerosis.
LDL的脂质过氧化修饰,除用作研究动脉粥样硬化的发生发展的机制外,还是一种研究脂质过氧化损伤和比较抗氧化剂的抗氧化效果及其作用机理的较为理想的模型。We think that oxidative modification of LDL is probably an ideal model for the study of lipoperoxidation, of the effect and the mechanism of antioxidant, as well as of the mechanism of atherogenesis.