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这些药物被称为抗胆碱能制剂和旨在阻止乙酰胆碱。These drugs are known as anticholinergic agents and are designed to block acetylcholine.

现阶段的处置以药物的症状治疗为主。Symptomatic treatment with dopaminergic and anticholinergic medications remains the mainstay at the present time.

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通过兔瞳孔实验和离体豚鼠回肠肌实验观察制备化合物的胆碱能活性。Using pupils of rabbits and ileal muscles of guinea pig, the anticholinergic activity of the compounds was tested.

这类药物应用非常广泛，但其抗胆碱能和镇静作用却很难被患者所耐受。These medications are widely used but their anticholinergic and sedative properties may not be well tolerated by patients.

本文报道了抗胆碱化合物的综合筛选方法和部分化合物的初筛结果。A complex method for the screening of anticholinergic compounds and some preliminary results of their applicaton are reported.

兔瞳孔实验和离体豚鼠回肠肌实验显示1和5有明显的抗胆碱活性。Compound 1 and 5 showed anticholinergic activity in mydriatic experiments of rabbits and tests of ileal muscles of guinea pig.

目的观察山莨菪碱衍生物的抗胆碱活性，总结其构效关系。OBJECTIVE To observe the anticholinergic activity of the derivatives of anisodamine and summarize the structure-activity relationship.

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研究人员发现，较高的抗胆碱能负担的方法，是与更糟的身体机能，无论是自报和业绩为基础的。The researchers found that higher anticholinergic burden is associated with worse physical function, both self-reported and performance-based.

镇静，嗜睡，头晕，不安协调，胃肠不适，支气管分泌物，抗胆碱作用，在儿童兴奋增厚。Sedation, sleepiness, dizziness, disturbed coordination, GI upset, thickening of bronchial secretions, anticholinergic effects, excitability in children.

如果孩子的膀胱痉挛的话，可以服用抗胆碱药物来治疗，如果孩子是缺乏抗利尿激素的话，可以服用合成激素。Children whose bladders tend to spasm can be treated with anticholinergic drugs, and children who lack an antidiuretic hormone can take a synthetic version.

综述了近年来抗胆碱能药物设计合成在阻断基团设计、连接基团设计、阳离子头设计方面的研究进展。The progress in devising synthesis of anticholinergic drugs is reviewed in the aspects of interdiction group, link group and cation group with 32 references.

常规剂量的滕喜隆或新斯的明等抗组胺药联合适量的抗胆碱药可以很好的拮抗。Antagonism can be easily accomplished by conventional dosages of edrophonium or neostigmine administered in conjunction with the appropriate anticholinergic agent.

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结论盐酸戊乙奎醚是抢救重度急性有机磷农药中毒比较理想的抗胆碱药物。Couclusion Pnehyclidine hydrochloride as an safe anticholinergic drug can replace atropine during the treatment of severe acute organophosphorus pesticide poisoning.

卓夫组的不良反应较氯丙嗪组少，其中锥体外系和抗胆碱能的不良反应发生率显著少于氯丙嗪组。Side effects in the risperidone group were fewer than in the chlorpromazine group, and especially the rates of extrapyramidal and anticholinergic side effects were lower.

文献纳入规范研究吸入抗胆碱能药物疗治COPD的随机对照试验，药物疗治时间不少于30天，而且报道有心思和精力管不良事件。Study Selection Randomized controlled trials of any inhaled anticholinergic for treatment of COPD that had at least 30 days of treatment and reported on cardiovascular events.

胆碱脂酶抑制剂和抗胆碱能药的合用，也可以解释中和肌松剂时，气道阻力没有增加。The co-administration of an anticholinergic with the anticholinesterase for the reversal of neuromuscular blockade may explain why increases in airway resistance do not occur.

结果发现，年龄、性别、抗胆碱能药物、用药总时间和目前用药量等五个因素在0．05或0．01水平上对TES的存在有显著意义上的作用。It was found suggest that age, gender, anticholinergic drugs, treatment duration and current dosage as the risk factors have significant effects on the existence of TES at 0.05 or 0.01 level.

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苯海，氨乙醇，组织胺受体1型阻滞剂著抗碱镇静特性，通阻碍神冲动传起某种程局麻醉。Ethanolamine class, histamine receptor type1 blocker. Has significant anticholinergic and sedative properties that causes some degree of topical anesthesia by impairing the transmission of nerve impu.