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倍体类型及异倍体的含量与其预后相关。The DNA ploidy types and aneuploid was associated with prognosis.

本发明属于小麦非整倍体生物技术育种领域。The invention belongs to the field of wheat aneuploid biotechnics breeding.

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显性致死突变的效应比非整倍体胚胎的效应高。Theeffect of dominant lethal mutation is higher than that of the aneuploid.

另外还发现三倍体及非整倍体细胞的存在。In addition, triploid and aneuploid cells were also observed in some variants.

结果显示,CD34表达和DNA非整倍体的存在并不能提示短期临床疗效。CD34 expression and DNA aneuploid in AL can't anticipate the short-peroid clinical outcome.

显然,先天带有非整倍体或者后天容易出现非整倍体,都加速了癌症发生的过程。Being born aneuploid , or prone to aneuploidy, clearly accelerates processes that lead to cancer.

膀胱癌单发或多发不影响尿脱落细胞异倍体的出现。The simple or multiple bladder cancer will not influence the existence of the aneuploid in urine.

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晚代细胞染色体主要为异倍体,而早代细胞主要为二倍体。The chromosomes of Y cells were diploid at the early passages, but became aneuploid in the late passages.

与此同时,单倍体细胞逐渐减少,产生大量多倍体和非整倍体细胞。Meanwhile the ratio of haploid cell in the callus dropped gradually, and a lot of polyploid and aneuploid cells appeared.

除了正常染色体对以外,还存在有第二种同源染色体的非整倍体状态,被称为三体性。An aneuploid state in which a third homologous chromosome is present in addition to the normal autosomal pair is called trisomy.

事实上,整倍体的细胞核群体的细胞集落比那些非整倍体的细胞多而密集。In fact, the cell colonies from the euploid cell nuclei populations were larger and more dense than those from the aneuploid ones.

DNA倍体也与P21表达密切相关,异倍体肿瘤表达阳性率明显高于二倍体肿瘤。DNA ploidy was found associated with ras P21 expression, ras P21 positive rate was higher in aneuploid tumors than in diploid tumors.

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由此,在非整倍体染色体中进行过度表达或表达不足序列的精确检测会更容易实现。Hence, precise detection of the over- or underrepresentation of sequences from an aneuploid chromosome could be more readily achieved.

结果显示角化型基底细胞癌组有异倍体16例,毛发上皮瘤组30例均为二倍体。The results showed 16 of 30 specimens from keratinized type of basal cell epithelioma were aneuploid and 30 specimens from trichoepithelioma were all diploid.

毛发上皮瘤组30例均为二倍体,角化型基底细胞癌组有异倍体16例。Quantitative analysis of DNA content showed 30 speciments from trichoepithelioma were all diploid. While 16 of 30 specimens from keratinizing basal cell epithelioma were aneuploid.

因此,胎儿基因组中的染色体非整倍体对孕妇血浆中染色体序列的整体排列的定量扰动就不会很大。Hence, quantitative perturbations caused by an aneuploid chromosome in the fetal genome to the overall representation of sequences from that chromosome in maternal plasma would be small.

只不过后来的科学家未能从这些混乱的染色体当中找出一致的形式。事实上,典型癌细胞的基因组并不只是非整倍体而已,同时也不稳定,每隔几代就有所改变。But scientists could find no recurrent pattern to the chromosomal chaos—indeed, the genome of a typical cancer cell is not merely aneuploid but is unstable as well, changing every few generations.