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经气管内注射博莱霉素建立肺纤维化模型。Pulmonary fibrosis model was induced by intra-tracheal injection of bleomycin.

研究结果提示博来霉素A_6有可能用于肝癌化疗。These observations suggest that bleomycin A_6 may be useful in human liver cancer chemotherapy.

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博来霉素水解酶是生物体内通过脱氨基作用代谢博来霉素的重要酶类。Bleomycin hydrolase is an important enzyme to metabolize bleomycin via deamination in organisms.

方法选用SD大鼠72只，随机分为博莱霉素组、肺炎组及正常对照组。Methods 72 SD rats were divided randomly into bleomycin group, pneumonia group and control group.

BIS检测是用博莱霉素作突变剂，反应细胞对致突变剂的敏感性。However, BIS was to take bleomycin as a mutagen to reflect the sensibility of lymphocyte to the mutagen.

结论校正博来霉素法是一种较好的，能实际用于临床的常规测定NPBI的方法。Conclusion The corrected bleomycin assay is a better method to estimate the concentration of plasma NPBI.

本研究证实了该药抗肿瘤机制与其导致瘤细胞DNA单链断裂有关。The results demonstrated that DNA single-strand breakage relates to the anti tumor mechanism of Bleomycin.

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应用本方法对争光霉素引起P388白血病细胞DNA单链断裂效应进行了探讨。DNA single-strand, breakage following Bleomycin treatment of P388 cells was studied by the method in vitro.

正常对照组和博来霉素模型组注射等体积生理盐水。The rats in the normal control group and bleomycin model group were injected with the same volume of saline.

目的观察平阳霉素局部注射治疗睑黄疣的临床疗效。Objective To investigate the clinical effect of the treatment of bleomycin in patients with xanthelasma palpebrarum.

目的探讨格列卫对小鼠肺纤维化的干预机制。Objective To explore the inhibitory mechanism of Imatinib mesylate on pulmonary fibrosis induced by bleomycin in mice.

博来霉素是于1972年从轮丝链霉菌中分离的11糖肽抗肿瘤抗生素复合物。Bleomycin is a complex of 11 glycopeptide antitumor antibiotics originally isolated from Streptomyces verticillus in 1972.

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目的考察博莱霉素治疗颅咽管瘤的疗效、应用方式与副反应。Objective To explore the inhibitory effect, applied approach and relative complications of bleomycin on craniopharyngiomas.

争光霉素A-6对造血和免疫功能毒性很低，这种结合物可能较安全地用于白血病化疗。Since bleomycin A6 is less toxic to hemopoiesis and immune function, this conjugate might be more safer for leukemia chemotherapy.

目的探讨平阳霉素对颊囊癌金黄地鼠肺组织的毒副作用。Objective To investigate the toxic effect of Bleomycin A5 on golden hamster's pulmonary tissue which carried buccal pouch carcinoma.

目的探讨阿奇霉素对博莱霉素所致大鼠肺间质纤维化的干预作用及机制。Objective To evaluate the therapeutic effects and mechanism of azithromycin treatment in bleomycin induced pulmonary fibrosis of rats.

目的探讨博莱霉素致肺纤维化的影像学表现与血管内皮细胞病理学问的关系。Objective To explore the correlation between imaging of bleomycin induced pulmonary fibrosis and pathology of microvessel endothelial cells.

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目的观察化纤方对博莱霉素所致肺纤维化大鼠肺组织形态学的影响，探索其阻抑肺纤维化的效应与机制。Objective To investigate the effects of "Hua Xian Fang" on pulmonary fibrosis and pulmonary coefficients in rats induced by bleomycin and explore its mechanism.

结论博莱霉素-碘化油乳剂靶肺气道栓塞术可形成肺不张、纤维化，达到FPLT目的。Conclusion Intrabronchus embolization with bleomycin lipiodol emulsion can result in atelectasis and fibrosis of the target pulmonary lobes, so it is an effective method for achieving FPLT.

结果表明，肝素加可的松混合液结膜下注射防治兔角膜新生血管的作用优于平阳霉素。The results show that the effect of subconjuctival injection of heparin combined with cortisone into experimental rabbits to prevent vascularization of cornea is better than that of bleomycin.