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其中杂环部分常为嘧啶环或均三嗪环。Heterocycle is always pyrimidine or triazine.
海嘧啶可显著降低肿瘤细胞膜钙泵活性。Sea pyrimidine can decrease the activity of calcium pump of tumor cells.
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嘧啶环广泛存在于自然界,是生命系统必须的分子结构单元。Pyrimidine rings, as the essential structure unit in biological systems, exist widely in nature.
采用气相色谱法对2-氨基-4,6-二甲基嘧啶进行了分析方法的研究。A gas chromatography method for the quantitative of 2-amino-4, 6-dimethyl pyrimidine is described.
以乙酰丙酮及尿素为主要原料合成4,6-二甲基-2-羟基嘧啶中间体,再与氯乙酸反应合成4,6-二甲基-2-羧甲氧基嘧啶。Then the intermediates reacted with chloroacetic acid to synthesize 4,6-dimethyl-2-carboxy methoxy pyrimidine.
拉米夫定是一种嘧啶核苷类抗病毒药物,主要用于慢性乙型肝炎的治疗。Lamivudine is a typical antivirus agent of pyrimidine nucleoside, mainly used for the treatment of hepatitis B.
嘧啶环5位的胞嘧啶甲基化是大部分生物体中一个主要的DNA甲基化修饰。Methylation of cytosine in the 5 position of the pyrimidine ring is a major modification of the DNA in most organisms.
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嘧啶衍生物的合成与转化、生物活性与代谢研究是有意义的。Studies on the synthesis and conversions, biological activity and metabolism of pyrimidine derivatives are significant.
嘧啶核苷包括尿嘧啶核苷和胞嘧啶核苷,其在食品工业和医药行业上应用广泛。Pyrimidine includes cytidine and uridine, which has a wide range of applications in the food and pharmaceutical industries.
本文比较可分解及不可分解放射性标帜嘧啶核苷酸之个别优点。The relative merits between "degradable" and "non-degradable" radiolabeled pyrimidine analogues have been compared in this paper.
在医药工业中,可用于制造头孢菌素V、磺胺-6-甲氧嘧啶、磺胺邻二甲氧嘧啶、氟胞嘧啶等。In medical industry, it is used in the production of cephalosporin V, sulfanilamide -6- methoxamine pyrimidine, fluorine pyrimidine.
人们设计了用来模拟光解酶作用的模型化合物,例如将一个发色团共价连接到一个嘧啶二聚体上。Several model compounds that mimic the action of photolyase have been designed, such as a chromophore attached to a pyrimidine dimer.
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一种简单的含氮有机分子,具一个双环结构——六元嘧啶环融合成一个五元咪唑环。Purine A simple nitrogenous organic molecule with a double-ring structure ? a 6-membered pyrimidine ring fused to a 5-membered imidazole ring.
三种n-氯乙酰取代的苯并含氮杂环化合物通过硫醚键的形成被导入嘧啶结构。Three types of N? chloroacetyl substituted nitrogen? containing benzoheterocycles were introduced into pyrimidine by the formation of thioether.
胸腺嘧啶脱氧核苷亦可能是茶叶中的嘧啶类生物碱与微生物中的核苷类化合物在后发酵过程中缩合形成的。On the other hand , deoxythymidine might be derived from the combination of pyrimidine alkaloid in tea leaves with microbial secondary metabolite.
一种嘧啶核苷类抗菌素和丙环唑复配杀菌剂,属于农药技术领域。The invention discloses a pyrimidine nucleoside antibiotic and propiconazole compound bactericide, which belongs to the technical field of pesticide.
结论嘌呤核苷酸可诱导肠上皮细胞凋亡,嘧啶核苷酸UMP可解除嘌呤核苷酸的凋亡诱导作用。Conclusion Purine nucleotides induce apoptosis of IEC-6, pyrimidine nucleotides UMP could abolish the apoptosis-inducing effects of purine nucleotides.
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结论海嘧啶抗肿瘤的药理机制与其能够抑制肿瘤细胞膜钠泵活性有关。Conclusion The anti-tumor pharmacologic mechanism of the sea pyrimidine is related to its decreasing the activities of sodium pump at tumor cells membranes.
酰基硫脲嘧啶类化合物制备简易,生物活性广泛,在杀虫、杀菌、除草及植物生长调节等方面均有重要应用。Acylthiourea pyrimidine derivatives are easy preparation and have broad biological activity, such as, insecticidal, fungicidal, weeding, and regulation of plant growth.
以烷基苯乙酮为原料通过一系列反应制备出新一类嘧啶液晶,对其性能进行了测试。A new class of pyrimidine liquid crystals was synthesized through a series of reaction with benzene acetophenone as the raw material, and their performances were tested.