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达比加群是一种直接凝血酶抑制剂。We could use dabigatran. Dabigatran is a direct thrombin inhibitor.

血小板释放的一种酶，能在血液开始凝结时将凝血素转化为凝血酶。A plasma protein that is converted into thrombin during blood clotting.

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血浆中凝血酶是近年开发的一种新型止血剂。Thrombin in blood is a new haemostatic which is exploited in recent years.

凝血酶经CM离子交换液相层析柱进一步纯化。Thrombin was further purified with CM ion-exchange liquid chromatographic column.

当组织损伤时，释放出凝血致活酶，把凝血酶原变成凝血酶。When the tissue damage, the release of thromboplastin to prothrombin into thrombin.

文章就凝血酶的一般特性和其神经毒性作用作了综述。The article reviews the general characteristics of thrombin and its neurotoxic effects.

换句话说，当蛋白C通路被激活后，使纤维蛋白酶与血栓调节素结合。In other words, the protein C pathway, when activated, binds thrombin to thrombomodulin.

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结论凝血酶对丘脑组织具有毒性损伤作用，但这一损伤可被水蛭素逆转。Conclusion Damage to the thalamic tissue might be caused by thrombin and reversed by hirudin.

方法利用超声引导下凝血酶注射法治疗假性动脉瘤25例。Methods Ultrasound-guided thrombin injection for the treatment of pseudoaneurysms in 25 cases.

该药能够克服现用药物出血的缺点。因为BB-10153是由凝血酶激活的。BB-10153 is an engineered variant of human plasminogen that is activated to plasmin by thrombin.

方法采用泮托拉唑联合凝血酶治疗36例上消化道出血患者。Methods Pantoprazole treated 36 upper gastrointestinal bleeding patients combining with thrombin.

分析PA的形状、大小、颈部长度与宽度、凝血酶剂量、治疗结果以及并发症。PA form, size, neck length and width, thrombin dose, therapic effect and complications were analysed.

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PRC和移植材料保存在培养孔中，被额外的胎牛血小板所凝聚。PRC and graft materials were retained within well inserts and clotted by addition of bovine thrombin.

能完全抑制由凝血酶和瑞斯托霉素诱导的血小板聚集。Additionally, thrombomodulin can entirely inhibit thrombin and ristocetin-induced platelet aggregation.

内源性凝血酶是一种神经毒性物质，可引起脑组织一系列的病理生理学改变。The endogenous thrombin is a kind of neurotoxic agent which causes a series of pathophysiological changes.

目的探讨凝血酶对丘脑组织是否具有毒性损伤作用以及损伤是否可逆。Objective To investigate the toxic damage Jn thalamic tissue mused by thrombin and whether can be reversed.

结论纤维蛋白加凝血酶对治疗难治性气胸是安全，有效的方法。Conclusion Fibrin plus thrombin is safe and effective for treatment of patients with re-fractory pneumothorax.

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报道了一种酶促-化学法合成光学纯吗啉酮凝血酶抑制剂的新途径。A new synthetic method of thrombin inhibitor based on morpholinone was accomplished by a chemoenzymatic approach.

为便于从融合蛋白中解离出目的多肽，这个载体中含有特异的蛋白酶裂解位点。This vector also contains thrombin protease cleavage site to facilitate proteolysis of the bacterial fusion proteins.

利用监测散射变化和扫描电子显微镜等手段表征了酶活性的变化。Real-time light scattering spectroscopy and scanning electron microscopy have been used to determine thrombin activity.