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建议进行类毒素强化注射。Toxoid booster injections are recommended.

市售马抗破伤风血清经标记后效果满意。The commercially supplied horse anti-tetanus toxoid serum was used satisfactorily.

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最后评价了载破伤风类毒素微球的免疫效果。Finally the immunogenicity of tetanus toxoid encapsulated in the microspheres was evaluated.

因此，有针对地选用类毒素预防接种，才能防止本病流行。Therefore, using toxoid to make preventive inoculation can avoid spread of this infectious disease.

本文提供了用三种效力试验方法检定吸附精制破伤风类毒素的结果。This article presents the results of standardization of adsorbed purified tetanus toxoid by 3 potency test methods.

这种改良的类毒素在1940年代与破伤风以及百日咳结合之后开始广泛使用。Widespread use of this modified toxoid began in the 1940s when it was combined with the tetanus and pertussis vaccines.

在7种对氧磷人工抗原中，对氧磷-破伤风类毒素的免疫效果最好。Among the 7 artificial paraoxon antigens studied, we found that paraoxon-tetanus toxoid has the best immunologic effect.

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破伤风是由破伤风毒素引起的一种严重的痉挛性疾病，有效的预防方法是接种破伤风类毒素疫苗。Tetanus is a severe spastic disease caused by tetanus toxin, which can be prevented by immunization with tetanus toxoid.

以其免疫家兔，预防1个致死量对氧磷肌内注射染毒，14只兔全部存活。All the 14 immunized rabbits with paraoxon-tetanus toxoid survived after a challenge of 1LD of paraoxon injected intramuscularly.

用破伤风毒素和异硫氰酸荧光素标记马抗破伤风血清可以特异地显示体外培养的神经细胞。Tetanus toxin and FITC labelled horse anti-tetanus toxoid serum were applied to show the plasma membrane of cultivated chicken embryonic cerebral cortical cells.

研究不同剂量及不同白喉类毒素纯度引起的迟发型超敏反应的状况，用于指导疫苗的生产，提高疫苗的质量。The delayed hypersensitivity induced by the diphtheria toxoid with different purity and dose was investigated to guide the vaccine production and improve the vaccine quality.

目的研究破伤风类毒素聚乳酸微球中破伤风类毒素在制备过程和体内酸性环境中的稳定性及微球中附加剂的稳定作用。OBJECTIVE To investigate the stability of microencapsulated tetanus toxoid in the courses of preparation and release, and improve its stability by co encapsulation of additives.

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结论破伤风类毒素聚乳酸微球中的蛋白质在制备过程和体内酸性环境中基本稳定，聚乳酸微球可望发展成为疫苗控释系统。CONCLUSION The stability of tetanus toxoid loaded microspheres was satisfactory. The optimized tetanus toxoid containing microspheres may be valuable for a controlled vaccine delivery system.