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大细胞淋巴瘤会影响到免疫系统。The cancer, anaplastic large-cell lymphoma involves the immune system.

诊断为原发性皮肤间变性大细胞淋巴瘤。The pathologic diagnosis was primary cutaneous anaplastic large cell lymphoma.

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报告1例ALK-1蛋白阳性的原发性皮肤CD30+间变性大细胞淋巴瘤。A case of primary cutaneous CD30-positive anaplastic large cell lymphoma with ALK-1 positive is reported.

研究还指出隆胸手术和一种名为间变性大细胞淋巴瘤的罕见的癌症形式之间的细微联系。The research also showed a small link with a very rare form of cancer known as anaplastic large cell lymphoma.

术后病理按WHO分级分类，星形细胞瘤11例，间变型星形细胞瘤4例，少突胶质细胞瘤3例。According to WHO classification of glioma pathology, 11 were astrocytomas, 4 anaplastic astrocytomas and 3 olidendromas.

依据肿瘤分化程度，可分为分化型和间变型室管膜瘤。According to the de-gree of differentiation, the tumor could be divided into typical ependymoma and anaplastic ependymoma.

提示PKM2的基因治疗可能成为治疗甲状腺未分化癌和治疗其它特异性表达PKM2的恶性肿瘤的潜在新靶点。PKM2 can be a new useful target for gene therapy in anaplastic thyroid cancer and other cancer overexpressing PKM2 in future.

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⑶对于间变癌与淋巴瘤以及用放射性碘难以治愈的腺癌，我们选用外照射治疗。External radiation therapy is reserved for anaplastic carcinoma and lymphoma, and adenocarcinomas that are refractory to radioactive iodine.

结果间变性室管膜瘤好发于脑室系统，临床表现大多有颅内压升高症状。The result of anaplastic ependymomas occur in the ventricular system, most clinical manifestations are symptoms of intracranial hypertension.

再经过详细检查及评估之后，第二次手术才进行肿瘤切除，组织病理报告证实为脊髓内恶性星状细胞瘤。Two months later, a second subtotal cytoreductive surgery was performed and anaplastic intramedullary astrocytoma was proved by pathology results.

最常见的组织学类型依次是伯基特淋巴瘤、淋巴母细胞淋巴瘤、霍奇金淋巴瘤、间变性大细胞淋巴瘤和弥漫大B细胞淋巴瘤。The most common subtypes were Burkitt lymphoma, Lymphoblastic lymphoma, Hodgkin lymphomas, Anaplastic large cell lymphoma and Diffuse Large B-cell Lymphoma.

结果间变性星形细胞瘤7例，多形性胶质母细胞瘤3例，少突胶质瘤1例，低级别胶质瘤1例。Results There were 7 cases with anaplastic astrocytoma, 3 cases with glioblastoma multiforme, 1 cases with oligodendroglioma, 1 cases with lower grade glioma.

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结论间变性星形细胞瘤中普遍存在DR的高表达，这可能为间变性星形细胞瘤的凋亡诱导治疗提供新的靶点和新的策略。Conclusions High DR expression is prevalent in anaplastic astrocytoma tissues. This may contribute to the apoptosis-inducing therapy of anaplastic astrocytoma.

结论间变性星形细胞瘤细胞中普遍存在DR的高表达，这可能为间变性星形细胞瘤的凋亡诱导治疗提供新的靶点。Conclusions High DR expression is prevalent in anaplastic astrocytoma tissue and this may contribute to the apoptosis-inducing therapy of anaplastic astrocytoma.

一种恶性肿瘤，其特征为退化细胞侵入周围组织和向新的身体部位移转并大量增生。Any of various malignant neoplasms characterized by the proliferation of anaplastic cells that tend to invade surrounding tissue and metastasize to new body sites.

本病为最恶性的甲状腺癌，见于老年人，病理各异，包括纺锤状、鳞状和未分化细胞。This is a particularly virulent form of thyroid carcinoma. It occurs in the elderly and has a variable pathology, including spindle, squamous, and anaplastic cells.

大细胞间变性恶性淋巴瘤对MTX高敏，临床MTX使用剂量可相对减少，且维持用药时间也可略缩短。Patient with large cell anaplastic lymphoma possess high sensitivity to MTX, suggesting that the dosage of MTX may be scaled down, the time of usage may also be shortened.

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经典型霍奇金淋巴瘤、间变性大细胞淋巴瘤、神经鞘瘤、胸腺瘤和不同部位鳞癌的肿瘤性细胞常表达PD-L1。Also, the neoplastic cells of classical Hodgkin lymphoma, anaplastic large cell lymphoma, schwannoma, thymoma, and squamous cell carcinoma of various sites frequently expressed PD-L1.