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用ABC法免疫组化检测瘢痕疙瘩中新合成的胶原。New formed collagen in keloid was localized with ABC immunohistochemical staining.

结论P53蛋白能够抑制人瘢痕疙瘩成纤维细胞MMP1、MMP3蛋白的表达。Conclusion P53 can obviously inhibit MMP1 and MMP3 expression in human keloid fibroblasts.

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患者的年龄、性别、病灶大小及解剖位置分布与复发率高低无直接关系。Meanwhile, patient's age, sex, keloid size and location had no increased likehood of recurrence rate.

结论手术联合术后早期放疗是治疗瘢痕疙瘩的有效方法。Conclusion Operation combined with early postoperative radiotherapy is a effective method to treat keloid.

方法用中草药贴膏治疗疤痕增生和疤痕疙瘩患者共152例。Methods Treating 152 cases with scar proliferation and keloid with chinese medicinal herb adhesive plaster.

免疫组化染色显示瘢痕疙瘩中成纤维细胞有丰富的I型前胶原表达。Immunohistochemical staining showed increased expression of new formed, type I procollagen in keloid tissue.

目的探索瘢痕疙瘩误诊误治的原因，提高治疗效果。Objective To explore causes for misdiagnosis and mistreatment of keloid in order to improve curative effect.

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硅凝胶薄膜可用于治疗和预防瘢痕疙瘩和增生性疤痕，是用来对愈合的皮肤。Silicon gel sheeting can be used to treat and prevent hypertrophic and keloid scars and is used on healing skin.

在瘢痕疙瘩组织边缘，CTGF表达呈现由强至弱的过渡现象。Transitional phenomenon was observed from strong to weak expression of CTGF protein at the edge of keloid tissue.

目的检测国产PGA支架对瘢痕、皮肤和肌腱成纤维细胞增殖的影响。Objective To examine whether domestic-made PGA scaffold affects human tennocyte, keloid and skin fibroblast proliferation.

结论瘢痕疙瘩不同病理部位RUNX3的表达差异可能是导致瘢痕疙瘩呈浸润性生长的机理之一。Conclusion The difference in distributions of RUNX3 index may be one of the mechanisms accounting for the aggressive growth of keloid.

目的分析RUNX3蛋白在瘢痕疙瘩不同病理部位表达差异，以探讨瘢痕疙瘩呈浸润性生长的机理。Objective To explore the aggressive growth characteristics in invasive, proliferative, aged parts of keloid for analysis the RUNX3 index.

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现在我有一个瘢瘤疤也在用它，疤痕慢慢的退了，我希望这个去疤膏也能把我这个瘢瘤疤完全去掉。Now I have a keloid scar that im workin on. It´s going done slowly. I just hope the ointment disenegrate it all the way. This is real stuff.

本综述的目的就是研究瘢痕疙瘩在分子和细胞水平上和正常创伤愈合过程的关系的病原生物学。The aim of this review was to investigate the molecular and cellular pathobiology of keloid disease in relation to the normal wound healing process.

增殖性瘢痕组织中胶原蛋白的合成显著增加从而导致胶原的过度沉积。Overexpression of procollagen gene can cause the extraordinary increase of collagen's synthesis and therefore lead to the keloid and hypertrophic scar.

方法收集6个无亲缘关系的中国汉族瘢痕疙瘩家系的临床资料、绘制家系系谱和分析遗传模式以说明其遗传学特征。Methods The clinical data of 6 unrelated Chinese Han keloid pedigrees were collected, and their pedigree charts were constructed and the inheritance patterns analyzed.

根据瘢痕疙瘩的不同类型，在外科手术切除的基础上，选用术后放疗、局部加压、硅胶膜覆盖、糖皮质激素局部注射等多种方法予以治疗。On the basis of surgical excision, we applied postoperation radiotherapy, local compression, silicon gel covering and glucocorticosteroid injecting according to different keloid types.

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结论构建成功的含有TRADD基因片段的重组腺病毒，可用于转染人成纤维细胞，用于检测TRADD对病理性瘢痕成纤维细胞的影响。Conclusion The recombinant adenovirus vector carrying human TRADD gene was successfully constructed. It can be used for detecting the effects of TRADD on fibroblasts of hypertrophic scar and keloid.