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抗心律失常药物是治疗的主要手段。Antiarrhythmic drugs have been the mainstay of therapy.

第三个重点是关于抗心律失常治疗。The third important point is regarding antiarrhythmic therapy.

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目的研究离子通道病的特征及新靶点。AIM To investigate the pattern of ion channelopathies and the novel target of antiarrhythmic agents.

通过查阅近几年文献，综述了伊布利特的药理作用、药代动力学、临床应用和不良反应。The pharmacology, pharmacokinetics, clinical uses and side Affects of ibutilide, a new antiarrhythmic drug, were reviewed.

利多卡因一种合成氨化物，c14h22n2o，主要用它的盐酸盐作局部麻醉剂和抗。A synthetic amide, C14H22N2O, used chiefly in the form of its hydrochloride as a local anesthetic and antiarrhythmic agent.

在过去的25年里，没有新的抗心律失常药物出现，这是个遗憾，因为对此类药物需求很大。As you know, for 25 years we have not had any new antiarrhythmic drugs and that was a pity because there was an unmet need.

盐酸恩卡尼是一种新型的抗心律失常药。Encainide HCl is a new antiarrhythmic agent, The related substances of encainideHCI in its syntheic processes were studied.

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然而心室功能受损也使抗心律失常药更易出现毒副作用。However, patients with impaired ventricular function also have an increased risk of adverse effects from antiarrhythmic drugs.

所述应用是指含富马酸伊布利特的组合物在制备抗心律失常药物中的应用。The application refers to the application of the composition containing ibutililde fumarate in preparing antiarrhythmic drugs.

在开始进行抗心律不齐药物治疗前请咨询心脏电理学专家或者资深医师。Consultation with a cardiac electrophysiologist or knowledgeable physician is recommended prior to antiarrhythmic drug initiation.

确切的保护机制仍不清楚，然而，因为EPA有着抗高血脂、抗血小板、抗炎和抗心律不齐的作用。The exact mechanism remains unclear, however, because EPA has antihyperlipidemic, antiplatelet, anti-inflammatory and antiarrhythmic effects.

采用肾上腺素诱发清醒家兔心律失常和结扎冠状动脉造成麻醉大鼠心律失常模型进行药理试验。Its antiarrhythmic effect is evaluated in conscious rabbit and anesthetized rat models of arrhythmia induced by epinephrine and coronary ligation.

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最后，维持窦性心律所带来的益处也可能被抗心律失常药的毒副作用所消减。Finally, the possible benefit of sinus rhythm maintenance may be reduced by some of the harmful effects of currently available antiarrhythmic agents.

接受扩冠脉血管治疗3例，营养心肌治疗48例，抗高血压治疗31例，抗心律失常治疗19例。Three patients had coronary bypass surgery, 48 patients had cardiotonic , 31 had antihypertensive and 19 had antiarrhythmic therapies before surgery.

结论治疗心力衰竭并发心律失常纠正心功能不全是关键，权衡利弊合理应用抗心律失常药物。Conclusion Correction of heart function is the key point in the treatment of CHF accompanied by arrhythmia, and a rational use of antiarrhythmic advised.

实验结果提示布吡卡因能影响细胞膜上多种离子通道，具有广谱抗心律失常作用。The experimental results indicated that bupivacaine may influence various kinds of ionic channel on cell membrane with wide-ranging antiarrhythmic effects.

方法总结分析19例预激综合征伴房颤的急诊治疗措施与疗效。Methods We observed effects of antiarrhythmic agents and synchronized cardioversion treatment of atrial fibrillation in 19 patients with preexcitation syndrome.

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研究对象来自于法国的44个医学中心，共计6，319例序贯患者接受了抗心律失常电子装置的植入术。The study population comprised 6,319 consecutive patients who underwent implantation of an antiarrhythmic system at one of 44 participating medical centers in France.

妊娠期孕妇有着特殊的生理和药代动力学变化，妊娠期心律失常药物治疗有其特殊性和重要性，故临床用药应顾及胎儿安全。There are some particularity and importance for antiarrhythmic pharmacotherapy in pregnancy. More attention should be paid to safety of fetus in clinical pharmacotherapy.

治疗以改善心功能为主，多数心律失常病人在未用抗心律失常药物情况下，随着心功能的改善而明显减少或消失。The priority of treatment was to improve the heart function. Most arrhythmia relieved or disappeared along with the improvement of the heart function without antiarrhythmic.