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目的探讨红细胞生成素对小鼠化疗所致贫血的预防作用。Objective To investigate the prevention effect of erythropoietin on chemotherapy-induced anemia.

目的探讨促红细胞生成素在血液透析患者治疗过程中对脂质代谢的影响。Objective To investigate the effects of erythropoietin on the lipid metabolism in hemodialysis patients.

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目的探讨促红细胞生成素在子宫内膜异位症发生发展中的作用及其临床意义。Objective To investigate the expression of erythropoietin in endometriosis and its related clinical roles.

此外，在没有促红细胞生成素的血样中红细胞可以繁殖。Moreoer, erythroid colonies could be grown from blood samples without the need for exogenous erythropoietin.

此外，在没有促红细胞生成素的血样中红细胞可以繁殖。Moreover, erythroid colonies could be grown from blood samples without the need for exogenous erythropoietin.

上百万癌症和肾脏疾病患者服用ESA，这种人造荷尔蒙能提高红血球数量。Millions of cancer and kidney disease patients take ESAs, man-made versions of a human hormone called erythropoietin.

由于我们已经知道了这种生物学机制,因此我们能体外制造促红细胞生成素,并作为药品应用Because we've learned about that biology we've been able to make erythropoietin outside the body and use it as a drug.

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目的研究癌性贫血患者血清促红细胞生成素水平及其与血红蛋白含量之间的关系。Objective To study the relationship between levels of serum erythropoietin and haemoglobin in patients with anemia of cancer.

体外细胞培养及动物实验证明，促红细胞生成素对脑缺血损伤具有神经保护和治疗作用。It has been proved that erythropoietin has neuroprotective effect and therapeutic action on cerebral ischemia in vivo and in vitro.

本文对红细胞生成素及其受体的产生、结构及其在脑缺血中的保护机制进行综述。The article reviews the development of erythropoietin and its receptors, its structure and protective mechanism in cerebral ischemia.

大多数物种中，肾脏既是促红细胞生成素的感受器官又是产生的主要场所，所以慢性肾功能衰竭会导致贫血。In most species, the kidney is both the sensor organ and the major site of erythropoietin production, so chronic renal failure is associated with anemia.

有研究显示重组人红细胞生成素能抑制细胞凋亡和炎症反应，具有神经保护作用。It has been reported that recombinant human erythropoietin rhEPO could inhibit cell apoptosis and inflammatory reaction and possess neuroprotective role.

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结论使用凝胶法检查重组人红细胞生成素注射液中的细菌内毒素是可行的，可用细菌内毒素凝胶法代替家兔热原检查法。CONCLUSION The jel method of bacterial endotoxin test can be used to pyrogen test the endotoxin in recombinant human erythropoietin injection instead of rabbit.

其发病机制与恶性肿瘤分泌促红细胞生成素有关，也可能是胸腺瘤所致T细胞免疫功能紊乱所致。The pathogenesis related to the erythropoietin secretion from malignant tumors, while another factor might be the immunological disturbance of T-lymphocyte caused by thymoma.

促红细胞生成素亦可以有效的提高化疗后荷瘤动物的红细胞免疫功能，其作用和剂量亦无明显相关。The erythropoietin can also improve the erythrocyte immune function of bearing tumor animal effectively after the chemotherapy and there is no dose-effect relationship either.

相反的，在视网膜病变血管新生期使用红血球生成素并不能保护血管，且可能恶化病理增殖作用。Conversely, the late use of erythropoietin during the neovascularization phase of retinopathy does not protect the vasculature, and also might exacerbate pathologic proliferation.

方法构建EDRF1真核正义和反义表达载体，转染HEL细胞并筛选稳定表达细胞克隆。Methods EDRF1 sense and antisense constructs were transfected into HEL cells, then the expression of globin and erythropoietin receptor gene was identified by Northern blot analysis.

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以基因转植增加红血球生成素，已进行过动物试验，结果显示如果贸然在人体尝试，将会引发潜在的危险。Gene transfer to raise erythropoietin production has already been tried in animals, with results that illustrate the potential dangers of prematurely attempting such enhancements in humans.

方法应用鲎法检查重组人红细胞生成素注射液中的细菌内毒素，考察重组人红细胞生成素注射液对细菌内毒素检查法的干扰。METHODS Limulus reagent was used to detect pyrogen in recombinant human erythropoietin injection, to observe interference of recombinant human erythropoietin injection to bacterial endotoxin test.