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疏水性分析证明其可能构成一个表位。Hydrophobic cluster analysis showed that the peptide was likely to form an epitope.
结论通过首位串联可以实现HEV线性表位较高效的表达。ConclusionHigh level expression of epitope from HEV could be achieved by tandem repeats.
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方法采用基于表位的疫苗设计方法,用化学合成的方法制备该种分子。Epitope based vaccine design is adopted and chemical method is used to synthesis target genes.
简要介绍了表位附加标记的概念、应用、优缺点及其发展前景。This paper described the definition, application, advantages and weaks of epitope tagging briefly.
本论文工作主要集中在艾滋病重组表位疫苗的设计原理和制备技术方面的研究。Here, we have focused on the design and construction of the recombinant epitope vaccine against HIV.
竞争抑制实验表明所获人源抗体片段与亲本鼠源单抗结合同一抗原表位。Binding competition studies demonstrated that they bound the same epitope of the Ag as the parental Ab.
叠加实验表明,5A5、5C12和6F5三株单抗抗原识别位点均不相同。The results of superposable test suggest that 5A5, 5C12 and 6F5 were against different antigen epitope.
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目的从噬菌体12肽库中筛选卫氏并殖吸虫抗原模拟表位。Objective To screen the mimic antigen epitope of Paragonimus westermani from phage 12-mer peptide library.
研究法氏囊病毒VP2蛋白的抗原表位在机体免疫应答中的作用和特点。The research aimed to study the functions and characters of the antigen epitope of IBDV-VP2 protein in immune response.
酶修饰试验结果表明,ON_1D_3识别的抗原决定簇是唾液酸依赖性的。It suggests that the epitope of red blood cells recognized by ON_1D_3 secreting monoclonal anti-N was sialic acid dependent.
必须选择适合免疫共沉淀抗体识别目的蛋白表位的细胞裂解条件。The choice of lysis conditions must be tailored to the nature of the epitope recognized by the immunoprecipitating antibody.
目的探讨如何将人滋养层细胞促融合表位模拟肽构建成有效的避孕免疫原。Objective To explore how to arrange and construct trophoblast fusogenic epitope mimic peptide to obtain an effective immunogen.
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目的探讨卵巢癌抗独特型抗体6B11表位多肽与诱导免疫应答之间的关系。Objective To explore the relationship between the immune response induced by 6B11 anti-idiotypic antibody and its epitope peptides.
LIAI科学家理论上认为对抗原决定簇MHC结合的生物信息学预测方法同样适用于其他病毒。The LIAI scientists theorize that the bioinformatics prediction approach for epitope MHC binding will be applicable to other viruses.
经测序鉴定与原序列没有突变及移码后,经IPTG诱导,有四段含表位的多肽获得了表达。The constructed vector was identified by sequencing. After induction by IPTG, four polypeptides coding epitope expressed, respectively.
在免疫印迹、免疫沉淀和免疫染色等技术中,表位标签用于标记和检测蛋白。Epitope tags are useful for the labeling and detection of proteins using immunoblotting, immunoprecipitation, and immunostaining techniques.
抗鳗弧菌独特型单克隆抗体1E10是能够模拟鳗弧菌的保护性表位,可以作为疫苗使用的一种单克隆抗体。Anti-idiotype monoclonal antibody 1E10 can be used as vaccine for fish disease because it can mimic protective epitope of Vibrio anguillarum.
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将白色念珠菌特异表位基因插入到修饰后的质粒载体中,并制备了杂合噬菌体。A oligonucleotide encoding the specific epitope of Candida albicans was inserted to the above modified plasmid and the hybrid phage was purified.
基于表位的疫苗设计可以特异性的增强保护性免疫反应的强度,而排除非保护性以及抑制性免疫反应的影响。Epitope based vaccine design can promote the protective immune responses and exclude the effects of non-protective and inhibitory immune responses.
目的探讨DNA疫苗免疫接种方法对抗体水平及辅助性T细胞极化的影响。Objective To compare humoral immune responses and T helper cell polarization induced by different injection methods of a multi epitope chimeric DNA vaccine.