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利福平胶囊是一种高效“超广谱”的抗生素药物。Rifampicin Capsules is high efficacy broad-spectrum antibiotic.
最后一种被批准的一线结核病药物是20世纪60年代的利福平。The last first-line drug approved for TB was rifampicin in the 1960s.
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目的探讨利福平对血清胆红素测定的干扰。Objective To observe the interference of rifampicin on the determination of serum bilirubin.
采用HPLC紫外检测法测定给药后受试者血浆中利福平、异烟肼两种有效成分的浓度。The concentration of rifampicin and isoniazid in plasma was determined by the HPLC-UV method.
标准治疗涉及异烟肼和利福平正在考虑为至少为六个月。The standard treatment involves Isoniazid and Rifampicin being given for at least six months.
在1960年代初发现了联合化疗的另外两个组成部分,即利福平和氯法齐明。In the early 1960s, Rifampicin and clofazimine, the other two components of MDT, were discovered.
耐药谱很广,但对头孢唑啉、环丙沙星、丁氨卡那、利福平为高度敏感。Drug-sensitive test showed cefazolin, ciprofloxacin, amikacin, rifampicin were high sensitive drugs.
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一线药物包括异烟肼和利福平等,对结核病有比较好的治疗作用。First-line drugs, including isoniazid and rifampicin equality, there is relatively good for TB treatment.
利用抗利福平标记法研究拮抗芽孢杆菌B67在土壤及黄瓜根部的定殖情况。Colonizing of B67 isolate marked with Rifampicin on the soil and rhizosphere of cucumber were investigated.
异烟肼均具有良好的色谱行为。Results Ethambutol hydrochloride, isoniazid, pyrazinamide and rifampicin all had good chromatographic behavior.
目的探讨利福平增加异烟肼肝毒性的机制。Objective To study the mechanism of hepatic toxic injury induced by combining isoniazid with rifampicin in mice.
铜绿假单胞菌对氯霉素、利福平耐药严重,对环丙沙星仍较敏感。Pseudomonas aeruginosa was sensitive to ciprofloxacin, but its resistance to chloramphenicol and rifampicin was serious.
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比较环丙沙星或氧氟沙星联用抗结核药的肝毒性。To compare hepatic toxic injury induced by concomitant use of ciproxacin or ofloxacin and isoniazid and rifampicin in mice.
目的对2005版药典中利福平及其制剂质量标准中存在的问题进行探讨。Objective To discuss the problem in quality standard of Rifampicin and its preparation on Chinese Pharmacopoeia 2005 Edition.
结论口服利福平、吡嗪酰胺、静滴复方甘草酸单胺治疗布病安全有效,副作用小,复发率低。Conclusion To cure brucellosis by taking rifampicin and pyrazinamide orally and potenlin via veinous transfufusion is safe and effective.
耐多药结核是结核病的一种类型,由于对一线药物异烟肼和利福平具有耐药性,标准的治疗方法对其治疗效果不佳。MDR-TB is a form of TB that responds poorly to standard treatment because of resistance to the first-line drugs isoniazid and rifampicin.
利福平在硼酸盐或醋酸盐缓冲液中比在磷酸盐中稳定,磷酸盐可能促进利福平降解。The laboratory findings showed that rifampicin is more stable in borate or acetate buffer than in phosphate. Phosphate makes rifampicin to break up rapidly.
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目的考察聚乳酸相对分子量对利福平聚乳酸微球形态、载药量及微球中药物分布状态的影响。Aim To discover the effect of molecular weight of polylactic acid on the shape, drug content and drug distribution state of rifampicin polylactic acid microspheres.
分别采用差示-三波长分光光度法和单波长分光光度法测定复方利福平胶囊中的异烟肼及利福平。The differential three wavelength and the simple wavelength spectrophotometry were used for determining isoniazid and rifampicin respectively in compound rifampicin capsules.
历史悠久的抗结核药物利福平减缓了肝脏处理奈韦拉平的能力,让这种抗艾滋病药物效果更差,而且导致了病毒浓度的增加。The long-standing anti-TB drug rifampicin slows down the liver's ability to process nevirapine, making the anti-HIV drug less effective and causing an increase in virus levels.