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考察了一些手性化合物在该固定相上的拆分。Optical resolution of a range of racemic compounds was investigated.
用酵母进行了氧化拆分外消旋1,2-丙二醇的试验研究。This paper studied the resolution of racemic 1,2-propanediol with bakers yeast.
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第二,我们集中在伊普外消旋混合物的结晶动力学。Secondly, we focused on the crystallization kinetics of racemic compound of ibuprofen.
同时本论文也对拆分后的R型异构体进行转变消旋而重回收。At the same time, this paper also split the R-isomer of racemic to change and re-recovery.
然后拆分了各种外消旋醇,测定并计算热力学数据。Then various racemic alcohols were separated and their thermodynamic data were determined.
在这个部份,我们是伊普外消旋混合物的溶剂同质异相表的发明者。In this section, we are the inventors for the "form space" of the racemic compound of ibuprofen.
本文对部分化合物对映异构体的拆分机制进行了初步探讨。Mechanisms of the resolution of some of the racemic compounds on these bounded phases were proposed.
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目前,用于拆分外消旋化合物的酶多数是水解酶,而且绝大多数为脂肪酶。Presently, most of the catalysts used for the resolution of racemic mixtures are hydrolases, especially lipases.
在许多情况下,外消旋药物中的单一对映体分别具有不同的疗效,有的甚至有相反的作用。In many cases, racemic drug's single antipode has different curative effect, sometimes it even has adverse action.
本发明公开了一种利用醛催化制备消旋硒-甲基硒代半胱氨酸的方法。The invention discloses a method for preparing racemic selenium-methyl selenocysteine by using aldehyde catalysis.
提到生物催化,我们通常会想到外消旋物的动力学拆分和手性合成。When considering biocatalysis, terms like kinetic racemic resolution or chiral syntheses immediately come to mind.
利用脂肪酶在有机溶剂中催化对映选择性酯化反应对外消旋薄荷醇进行了有效的光学拆分。Optical resolution of racemic menthol has been efficiently achieved by lipase catalyzed enantioselective esterification in an organic solvent.
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可以使用立体选择或立体专一的合成方法,或者外消旋混合物的分离,来获得单独的光学异构体。Use of stereoselective or stereospecific synthetic methods or separation of racemic mixtures can be used to obtain individual optical isomers.
可治疗,作为推销消旋混合物是很好容忍至今未见任何互动与其他临床常用药物。Lescol, marketed as racemic mixture, is very well tolerated and to date has not shown any clinical interactions with other commonly used drugs.
两种对映体使偏振光向相反的角度旋转,彼此抵销,所以外消旋混合物没有光学活性。The two enantiomers rotate polarized light through opposite angles, canceling each other out so that the racemic mixture has no optical activity.
外消旋混合物的去消旋化是合成光学活性手性醇重要且实用的方法之一。Deracemization of racemic sec-alcohols is considered as one of the most important, fundamental and practical reactions for producing chiral sec-alcohols.
将所得聚合物用作高效液相色谱固定相,研究了它们对外消旋卡尼丁盐酸盐的拆分能力。The prepared polymers were applied as the liquid chromatographic chiral stationary phase to test their resolution ability for racemic carnitine hydrochloride.
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研究了微水有机溶剂两相体系中固定化脂肪酶催化的萘普生甲酯的立体选择性水解反应。A stereoselective hydrolysis of the racemic naproxen methyl ester by immobilized lipase from Candida rugosa in a low aqueous organic biphase system was studied.
有机相中应用酯化反应,酶法催化拆分消旋醇是获得光学活性醇的重要途径。The main route for obtaining optically active alcohols is resolution of racemic alcohols catalyzed by enzyme in organic solvents by the esterification reaction.
此外,还对酶膜生物反应器,尤其是其在对外消旋混合物手性拆分以及污水处理方面的应用作了简要的介绍。In addition, the applications of enzyme-membrane bioreactors, especially in the resolution of racemic mixtures and the treatment of wastewater, have also been briefly discussed.