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例如硫酸长春新碱、酒石酸长春瑞宪,NHDC。Such as Vincristine Sulfate, Vinorelbine Bitartrate, NHDC and Hesperidin Methyl Chalcone.
他们发现这种协同作用也发生在脂质体和长春新碱或紫杉醇。They also found that this synergy occurred with trastuzumab and either paclitaxel or vincristine.
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目的研究一种较好的微波和长春新碱的联合方法,用于白血病细胞的体外净化。Objective To study the method of microwave combined with vincristine for purging leukemic cells in vitro.
目的考察硫酸长春新碱脂质体的体外释放度及其药效。Objective To investigate the release rate and pharmacodynamics in vitro of of vincristine sulfate liposomes.
微波和长春新碱联合用于白血病细胞的体外净化能产生协同效应,值得进一步研究。The combination of microwave and vincristine showed a synergistic effect on purging leukemic cells in vitro.
治疗开端时出现粒细胞递减或血小板递减,并不表明不适用长春花碱。The presence of granulocytopenia or thrombocytopenia at the start of treatment does not contraindicate vincristine therapy.
长春新碱会给孩子带来严重的问题因为它会影响孩子们具有良好的精细运动速度的能力。Vincristine is one that causes acute problems for children because it has an effect on the ability to have good fine motor speed.
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方法用长春新碱、地塞米松组成VD方案治疗难治性特发性血小板减少性紫癜46例。Methods This study included 46 patients with refractory ITP treated with VD therapy which was composed of vincristine and dexamethasone.
目的优选分离纯化长春花中长春碱和长春新碱的最佳工艺参数。Objective To optimize the technological parameters of separation and purification of vinblastine and vincristine from Gatharanthus Roseus.
微管微丝动力学试验证实,S47能抑制微管微丝的聚合,与长春新碱作用机理相同。Microtubule dynamics test showed that S47 inhibited microtubule polymerization. Vincristine had a mechanism of action similar to that of S47.
结论该工艺简便合理,重复性良好,能得到高纯度的长春碱和长春新碱。Conclusions The process is simple and reasonable with good reproducibility. It is effective to enrich highly purified vinblastine and vincristine.
结论长春花内生真菌中,有的菌株可产生与宿主所产相同的抗癌物质长春新碱。Conclusion Some endophytic fungi isolated from C. roseus can produce the anticancer substance vincristine which is the same as that of host plant producing.
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但是一般在停用长春新碱之后,孩子们不再继续服用,大多数的机能会在几个月之内恢复正常。But typically after vincristine is finished and the child’s no longer getting it, within several months most of the functions return to normal at that point.
建立了HPLC法测定硫酸长春新碱和盐酸米托蒽醌复方脂质体的包封率。HPLC method was established for the determination of the entrapment efficiency of the liposomes loaded with vincristine sulfate and mitoxantrone hydrochloride.
建立了HPLC法测定硫酸长春新碱和盐酸米托蒽醌复方脂质体的包封率。A HPLC method was established for the determination of the entrapment efficiency of the liposomes loaded with vincristine sulfate and mitoxantrone hydrochloride.
恶性患者术后可辅以环磷酰胺、长春新碱、氮烯咪胺等化学药物治疗或131I-MIBG、123I-MIBG进行姑息性治疗。Palliative therapy involving cyclophosphamide, vincristine and dacarbazine have been conducted for malignant pheochromocytoma. 131I-MIBG and 123I-MIBG may also be used.
当孩子们服用长春新碱,我们很明显看到他们在学术和神经心理测试上表现变差。And we’ve clearly seen children’s performance in academic and on neuropsychological tests really be adversely or negatively affected when the child is getting the vincristine.
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所有患儿于放疗后接受长春新碱、环己亚硝脲、顺铂方案化疗,所有患者均未行鞘内化疗。Chemotherapy was given according to the protocol which consisted of lomustine, cisplatinum and vincristine after radiotherapy, but the patients were not given intrathecal chemotherapy.
在人肝细胞质膜、微粒体内存在有铜转运P型ATP酶,其阻滞剂及激动剂对肝细胞铜转运有显著影响。Copper transporting P type ATPase was found to be localized in human hepatocytic plasma membranes and microsomes, and sodium vanadte and vincristine can obviously change their copper transporting.