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奈西立肽是利用重组DNA技术得到的合成型人类脑利钠肽。Nesiritide is a synthetic form of brain natriuretic peptide using recombinant DNA technology.

目的探讨N-端脑钠肽前体在慢性阻塞性肺疾病中的变化及其意义。Objective To study the change and the significance of N-terminal pro-brain natriuretic peptide in the COPD patients.

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目的研究B型钠尿肽测定在充血性心力衰竭诊治中的作用。Objective To evaluate the diagnostic value of B-type natriuretic peptide for the patients with congestive heart failure.

年龄相关的血浆脑钠素在治疗24小时后升高，但不能预测心脏不利事件。Age-related plasma brain natriuretic peptide levels increased at 24 hours after ALB but did not predict cardiac adverse events.

蛋白信号亚单位4的调节因子介导心脏局部分泌钠尿肽的抗心肌肥厚效应。Regulator of G-Protein Signaling Subtype 4 Mediates Antihypertrophic Effect of Locally Secreted Natriuretic Peptides in the Heart.

重组人脑利钠肽是模拟内源性B型钠尿肽发挥生理作用的。The recombinant human B-type natriuretic peptide produces physiological effects by imitating endogenous B-type natriuretic peptide.

通过与利钠肽A型和B型受体结合，奈西立肽具有明确的扩血管和排钠利尿作用。Through combining natriuretic peptide receptors A and B, nesiritide possesser obvious vasodilatory, diuretic and natriuretic effects.

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由于心房利钠因子产生增加，房性快速性心律失常发作后常需排尿。Onset of atrial tachyarrhythmia is often followed by the need to urinate because of increased production of atrial natriuretic factor.

外源性的脑钠肽可以显著改善急性失代偿性心力衰竭的症状，已有相关药物问世。Exogenous brain natriuretic peptide can significantly improve acute decompensated heart failure symptoms, related drugs already available.

心钠素是由28个氨基酸组成的多肽，是一种安全有效、具有良好应用前景的新型药物。Atrial natriuretic peptide is a 28-amino-acid polypeptide, is one kind of new secure and effective, has the good application prospect medicine.

目的探讨B型钠尿肽测定在慢性舒张性心衰和无症状性心衰中的临床意义。Objective To evaluate the clinical significance of B-type natriuretic peptide in chronic diastolic heart failure and asymptomatic heart failure.

由于强烈的钠的作用，呋塞米注射液，钠水平可以减少，尤其是如果水肿是减少很快。Because of the strong natriuretic effect of Furosemide injection, the sodium levels could be reduced especially if the oedema is reduced quickly.

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目的观察新生儿窒息后血清心钠素及血糖水平的变化，为临床治疗提供依据。Objective Observing the changes of the levels of serum atrial natriuretic peptide and blood sugar in newborn after asphyxia to provide basis for clinical therapy.

静脉注射重组人脑利钠肽能迅速降低急性心力衰竭患者的肺毛细血管楔压，缓解呼吸困难症状，改善预后。Intravenous recombinant human B-type natriuretic peptide can quickly degrade pulmonary capillary wedge pressure, relieve dyspnea, and improve a patient's prognosis.

次要的结果包括心肺血流动力学、功能分级、随访期间的临床恶化，B型钠尿肽的死亡率和变化。Secondary outcomes included cardiopulmonary haemodynamics, functional class, clinical worsening during follow-up, mortality and changes in B-type natriuretic peptide.

新上市的脑啡肽酶抑制剂由于在利钠肽系统中所起的作用已经在医生和检验师中间产生巨大的影响力。New-on-the-market neprilysin inhibitors already have generated significant interest among physicians and laboratorians because of their effect on the natriuretic peptide system.

基因重组人心钠肽与内源性心钠肽具有相同的生物学作用，对急性心力衰竭的治疗已经显示出良好的效果。Recombinant human atrial natriuretic peptide has the same biological action as atrial natriuretic peptide in plasma, and has displayed positive effects in acute heart failure therapy.

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利尿药治疗的新理念、精氨酸加压素受体拮抗药、利钠多肽类似物、超滤等是心力衰竭排钠利尿治疗中的新进展。The new ideas for diuretics, arginine vasopressin receptor antagonist, natriuretic peptides analogues and ultrafiltration are new advances of natriuresis in the treatment of heart failure.