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有几个选项,以提供胞嘧啶基因。There are several options to deliver the cytosine gene.
腺嘌呤和鸟嘌呤是嘌呤和胞嘧啶和胸腺嘧啶是嘧啶。Adenine and guanine are purines and cytosine and thymine are pyrimidines.
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美国普渡大学的研究人员使用的是合成的鸟嘌呤与胞嘧啶。Researchers at Purdue University used synthetic forms of guanine and cytosine.
理论表明,卵子的DNA通过胞嘧啶甲基化过程进行了重组。Its DNA is reprogrammed, the theory goes, by a process called cytosine methylation.
形成Z-DNA通常需要一段交替出现的胞嘧啶与鸟嘌呤碱基。To make Z-DNA typically requires a stretch of alternating cytosine and guanine bases.
方法以胞嘧啶为起始原料,经六步反应合成西多福韦。Methods Cidofovir was synthesized via 6-step reactions with cytosine as the starting material.
胞苷一种白色的晶状核苷,c9h13n3o5,由每个。A white, crystalline nucleoside, C9H13N3O5, composed of one molecule each of cytosine and ribose.
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工作小组关注甲基化作用,是指一个甲基群被放在DNA序列的胞嘧啶上面。The team looked at methylation, in which a methyl group is placed onto cytosine in DNA sequences.
这些甲基团只粘附于特定胞嘧啶碱基-DNA四个组成成分之一。The methyl groups are attached only to specific cytosine bases — one of the four building blocks of DNA.
目前,最活跃的研究领域涉及引进一个胞嘧啶基因进入肿瘤细胞。Currently, the most active area of research involves introducing one of the cytosine genes into the cancer cell.
在某些噬菌体中,5-羟甲基胞嘧啶取代了胞嘧啶。40年代后期,查加夫。In certain bacteriophages, 5- methylol cytosines have substituted for the cytosine. In the late 40s, looks up Garv E.
胞嘧啶的环呼吸振动频率随着电位负移而红移,这意味着它与金电极的成键作用减弱。The binding interaction between cytosine and the gold electrode was weakened when the potential was negatively moved.
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嘧啶环5位的胞嘧啶甲基化是大部分生物体中一个主要的DNA甲基化修饰。Methylation of cytosine in the 5 position of the pyrimidine ring is a major modification of the DNA in most organisms.
胞嘧啶的甲基化能够沉默植物、脊椎动物和真菌的转座元件,同时也能调控基因的表达。Cytosine methylation silences transposable elements in plants, vertebrates, and fungi but also regulates gene expression.
此前,科学家们已对第5种碱基有所了解——当一个化学标签或甲基被固定到一个胞嘧啶上时,第5种碱基就会出现。Much is known about the "fifth base, " 5-methylcytosine, which arises when a chemical tag or methyl group is tacked onto a cytosine.
RNA能增强高三尖杉酯碱联合小剂量阿糖胞苷对K562细胞增殖的抑制作用。RNA could intensify the inhibitory effect of homoharringtonine and low-dose of arabinsyl cytosine on the cell proliferation of K562 cells.
他们在实验室内扩增间充质干细胞数量,然后利用逆转录病毒载体将胞嘧啶脱氨酶基因插入细胞基因组中。They expanded the number of mesenchymal stem cells in the laboratory and then used a retrovirus vector to insert the gene cytosine deaminase into the cell.
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随后PCR和独特扩增产物的序列分析在独特基因组序列上显示每个胞嘧啶残基的甲基化程度,位置,和序列环境。Subsequent PCR and sequence analysis of individual amplicons displays the degree, position, and sequence context of methylation of every cytosine residue in individual genomic sequences.
本文首次运用MSAP技术对脐橙品种进行胞嘧啶甲基化分析表明,使用MSAP检测脐橙品种多态性非常有效。This paper is the first time to analyse cytosine methylation in navel oranges using MSAP, indicating MSAP technique is efficient for detection of cytosine methylation in navel orange genomes.
哺乳动物似乎具有利用胞嘧啶甲基化提供一个可继承的机制,用来改变DNA-蛋白质相互作用,辅助这个沉默。Mammals appear to have taken advantage of the possibilities afforded by cytosine methylation to provide a heritable mechanism for altering DNA-protein interactions to assist in such silencing.