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本品是一种血管紧张素转换酶抑制剂。This drug is an angiotensin converting enzyme inhibitor.

这种药物阻断肾素-血管紧张素系统的机制不同于其他药物。The mechanism by which they block the renin- angiotensin system is different.

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受体阻断器是针对具有高水平血管紧缩素Ⅱ的心血管疾病患者经常采用的治疗方法。Receptor blockers are commonly used in cardiovascular patients who have high levels of angiotensin II.

肾素是一种单一特异性酶,是催化血管紧张素II合成的限速酶。Renin is a monospecific enzyme that catalyzes the rate-limiting step in the synthesis of angiotensin II.

目的探讨肾素血管紧张素醛固酮系统在甲亢性心脏病发病中的作用。Objective To study the role of renin angiotensin aldosterone system in the pathogenesis of hyperthyroid heart disease.

该基因影响血管紧缩素受体系统,该系统在雄性橙腹田鼠的社会化一夫一妻行为中起关键作用。This gene affects the angiotensin receptor system that plays a critical role in social monogamy for male prairie voles.

结论ET与肾功能、血压及紧素一血管紧张素一醛固酮系统关系密切。Conclusions The increase of plasma ET 1 may have an intimate relation to renal function and renin angiotensin aldosterone system.

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它会阻止的升压剂,血管紧张素Ⅱ,在血管平滑肌和肾上腺中对AT1受体结合。It blocks the binding of the pressor agent, angiotensin II, to the AT1 receptors in vascular smooth muscle and in the adrenal gland.

丙泊酚抑制肾素血管紧张素系统可能是其对血液动力学抑制的机制之一。Propofol can inhibit rennin angiotensin system, which may be one of the mechanisms responsible for hemodynamic depression of propofol.

分析可能与术后交感肾上腺系统、肾素-血管紧张素系统激活或术后输液过多过快等因素有关。It is thought that these changes are relative to postoperative activation of sympathetic adrenergic system and renin- angiotensin system.

目的本研究旨在观察沙坦类药物代谢酶CYP2C9和反应受体AT1的遗传多态性在高血压患者中的分布特征。Objective To investigate the genetic polymorphism of sartan drug metabolic enzyme CYP2C9 and angiotensin AT1 receptor in hypertensive patients.

研究证明,对血管紧张素转换酶进行抑制能有效地降低高血压患者的血压。It is confirmed that, inhibiting the activity of Angiotensin I-Converting Enzyme can lower the blood pressure in hypertensive patients potently.

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目的本研究旨在观察沙坦类药物代谢酶CYP2C9和反应受体AT1的遗传多态性在高血压患者中的分布特征。Objective To investigate the genetic polymorphism of spartan drug metabolic enzyme CYP2C9 and angiotensin AT1 receptor in hypertensive patients.

肾素血管紧张素系统在调节血压和水、盐代谢中发挥着重要作用。The rennin angiotensin system had been recognized for many years as a key regular of systemic blood pressure and the metabolism of water and salt.

阿利吉仑降低血浆肾素活性,抑制血管紧张素转化为血管紧张素,在血压下降造成的。Aliskiren reduces plasma renin activity and inhibits the conversion of angiotensinogen to angiotensin I, resulting in a decrease in blood pressure.

这种酶催化的血管紧张素一血管紧张素血液中的血浆和内皮二,防止故障的激肽转换。This enzyme catalyses the conversion of angiotensin I to angiotensin II in the blood plasma and endothelia and prevents the breakdown of bradykinin.

人类与小鼠酶系相同,肾素——血管紧张素途径对这二物种的血压和体液调节起着关键作用。Humans and mice have the same enzyme system, the renin- angiotensin pathway, which is crucial in both species for blood pressure and fluid regulation.

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结论肾素血管紧张素醛固酮系统激活是甲亢性心脏病发病的重要原因之一。Conclusion Hyperthyroidism results in activation of renin angiotensin aldosterone system which contributes to the pathogenesis of hyperthyroid heart disease.

然后血管紧张素I在血管紧张素转换酶作用下变为血管紧张系II,血管紧张素转换酶是一种位于肺部血管内皮的含锌酶。Angiotensin I is then cleaved to form active angiotensin II by ACE, a zinc-containing enzyme located in the endothelial lining of the vasculature of the lungs.

对昆嵛山血管紧张素转换酶抑制剂原料植物资源进行调查,为该资源的开发利用提供基础资料。The raw materials plant resources of angiotensin converting enzyme inhibitor were investigated, which provided basic data for the exploitation of these resources.