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使用蒽环类药物阿霉素是限制其心脏毒性。The use of the anthracycline doxorubicin is restricted by its cardiac toxicity.

研究化疗药物阿霉素在磁性纳米微球表面的吸脱附行为。The adsorption behavior of chemotherapy doxorubicin on magnetic nanoparticles was studied.

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目前，索拉非尼和多柔比星联用还不适合作为常规临床应用。The combination of sorafenib and doxorubicin is not yet indicated for routine clinical use.

在它的帮助下，研究者们可以向体内注射更大剂量的链霉素，而不会引起毒性反应。The researchers were able to inject the mice with doses of doxorubicin that normally would be lethal.

目的探讨减轻蒽环类化疗药物在治疗过程中所致局部不良反应的护理方法。Objective To probe the nursing method, abate the local side reaction of chemotherapy with doxorubicin.

这可能意味着索拉非尼与多柔比星具有协同作用，其引起的改善程度仍未确定。The degree to which this improvement may represent synergism between sorafenib and doxorubicin remains to be defined.

继而又转化成提高阿霉素这类作用于细胞内位点药物的治疗效果。This translates into enhanced therapeutic efficacy for drugs like doxorubicin that have intracellular site of action.

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目的探讨磁性阿霉素隐形脂质体靶向治疗裸鼠移植性人胃癌的疗效。Objective To study the effect of magnetic doxorubicin stealth liposome on human gastric cancer xenografts in nude mice.

结论磁性阿霉素隐形脂质体作为一种新型抗肿瘤药物显示了良好的应用前景。Conclusion Magnetic doxorubicin stealth liposome as a new anti-tumor drug carrier may have a favorable clinical prospect.

目的制备阿霉素高聚物胶束并研究其体外抗肿瘤活性。OBJECTIVE To prepare doxorubicin loaded N-octyl-N'-succinyl chitosan micelles and study the in vitro anti-tumor activity.

目前还没有2期或3期试验对索拉非尼与多柔比星联用治疗晚期HCC患者进行评价。The combination of sorafenib and doxorubicin in patients with advanced HCC has not been evaluated in a phase 2 or 3 trial.

向细胞靶向递送脂质体抗癌药物阿霉素可以在体外获得更好的疗效。The targeted delivery of liposomal anticancer drug doxorubicin results in better therapeutic efficacy towards cells in vitro.

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目的评价脂质体阿霉素在复发性卵巢上皮性癌二线化疗治疗中的有效性和安全性。Objective To evaluate the efficiency and safety of liposomal doxorubicin in the treatment of recurrent epithelial ovarian cancer.

重要的是，他们观察到，当塞来昔布联合多柔比星或索拉非尼用药时，培养中的肝癌细胞出现更多的凋亡。Importantly, they also observed that when celecoxib was combined with doxorubicin or sorafenib, more HCC cells in culture were killed.

加大环磷酰胺、依托泊甙、多柔比星剂量，即大CHOP处方不能进一步改善疗效。The dose escalation of cyclophosphamide, etoposide and doxorubicin characteristic of the mega-CHOP regimen did not further improve the results.

目的研究冬桑胶囊不同剂量给药对阿霉素肾病大鼠肾脏结构和功能的影响。Objective To explore the effect of different dosage of Dongsang capsule on the structure and function of rat with nephropathy caused by doxorubicin.

细胞毒性研究显示，纳米粒包囊阿霉素比溶液型的细胞毒性明显偏高且持续时间更长。Cytotoxicity studies demonstrated that doxorubicin in nanoparticles resulted in significantly higher and more sustained cytotoxicity than drug in solution.

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方法采用尾静脉注射阿霉素的方法，建立实验性肾病模型，观察冬桑胶囊对大鼠体重、血液生化学指标的影响及对肾组织的病理改变。Method To establish nephritic model by injecting doxorubicin in caudal vein. Then the effect of Dongsang capsule on weight and blood indexes were observed.

目的探讨阿霉素对大鼠膈肌的损伤机制及川芎嗪对阿霉素致大鼠膈肌损伤的保护作用。Objective To explore the mechanism of doxorubicin in impairing diaphragm and to investigate the prevention of doxorubicin -induced diaphragm injury in rats.

阿霉素静脉注射8周造成扩张型心肌病模型，卡维地洛组给予口服卡维地洛8周进行干预。We used doxorubicin intravenously for 8 weeks to creat rabbit models of DCM, and in carvedilol group the rabbits carvedilol were orally given oral for 8 weeks.