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快速心房起搏可导致细胞内钙离子超载。RAP can induce calcium overload in atrial myocyte.
尼莫地平能阻止缺血心肌细胞钙超载的发展和加重。Nimodipine could prevent the calcium overload in ischemic myocyte.
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本文从心肌细胞肥大这个角度阐述阿托伐他汀对心室重塑的影响。In this text, we reviewed the effect of atorvastatin on the treatment of cardiac myocyte hypertrophy.
方法应用全细胞膜片钳技术记录兔心室肌单个细胞的电流。Method Ion currents of rabbit ventricular myocyte were recorded using the whole cell patch clamp technique.
所有的心肌细胞都能自律性的去极化和复极化。All cardiac myocyte are capable of spontaneous rhythmic depolarization and repolarization of their membrane.
心肌细胞具有复杂的信号网络,从而调节其心脏节律性的泵出功能中的作用。Cardiac myocyte hypertrophy and apoptosis have been implicated in the loss of contractile function during heart failure.
现主要从他汀类药物影响小G蛋白信号通路方面,阐述其抑制心肌细胞肥大的主要机制。This article reviews the main mechanisms of preventing cardiac myocyte hypertrophy via small GTP-binding proteins pathways.
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目的建立单个心房肌细胞的急性分离方法并记录其电生理特性。Objective To construct a method of isolating single guinea pig atrial myocyte and to measure its electrophysiological properties.
方法膜片钳全细胞记录技术记录应用花生四烯酸前后人心房肌细胞钠电流。Methods Patch clamp technique was used to record sodium cur- rent in human atrial myocyte before and after administration of intracellular AA.
观察各组家兔血清心肌酶学变化,并通过电镜形态学及原位末端标记法检测心肌细胞凋亡情况。Then we observe the change of myocardium enzymatic dynamics and detect myocyte apoptosis with electronic microscope and situ end labeling way.
方法酶解法分离豚鼠单个心室肌细胞,应用全细胞膜片钳技术记录延胡索乙素对豚鼠单个心室肌细胞钾电流的影响。Methods Enzyme digestion was used to isolate single ventricular myocyte and whole cell patch clamp technique was used to record potassium current.
目的研究HOE642对热缺血死亡大鼠颈部异位停跳心脏供体心肌细胞凋亡的作用。Objective To investigate the effect of HOE642 on cardiac myocyte apoptosis of the heterotopic heart transplantation of rat non heart-beating donors.
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从诊断的角度来看,其目标是即使在没有证据表明肌细胞坏死的情况下鉴别出ACS的病人。From a diagnostic standpoint, the aim is to try and develop biomarkers that identify patients with ACS, even when there is no evidence of myocyte necrosis.
心肌梗死大鼠心肌细胞增殖程度与心脏收缩功能呈正性相关,与舒张功能呈负性相关。Myocyte proliferation is positively correlated with heart systolic function, and negatively correlated with heart diastolic function in chronic heart failure.
如果心肌缺血时间过长,心肌细胞死亡,此时的电除颤只会产生无脉性电活动或心搏停止。Should myocardial ischemia continue too long, myocyte death occurs, and electrical shock after this will only result in pulseless electrical activity or asystole.
结论在小剂量范围内,沙棘总黄酮是一种不依赖钙离子内转运而增加心肌细胞收缩力,从而能有效改善心衰的中药。Conclusion Flavonoids of the traditional Chinese drug hippophae rhamnoids is effective in improving the contractile function of stretched cardiac myocyte in low dosage.
结果获得了具正常电生理活性的单个细胞及高阻封接的形成,成功记录了L-型钙流和延迟整流性钾流。As a result single guinea-pig atrial myocyte with normal electrophysiologic activity was obtained and its L-Ica and IK were successfully recorded with patch-clamp technique.
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因此如果能够采取治疗措施促进梗死区灌注血管重建和心肌细胞再生,将会明显改善心梗患者的预后。The major goal to improve post-infarction prognosis would be the stimulation of neovascularization and the enhancement of regeneration of cardiac myocyte within the infarct area.
在分离的LV上以相同方向、均匀的切片,使用无偏倚的立体学方法,评估心肌细胞核总数、每个心肌细胞的细胞核数。Isotropic, uniformly random sections were cut from theisolated LV, and the total number of myocyte nuclei and the average number of nuclei per myocyte were estimated using unbiased stereology.
以上提示缺血预适应处理能减轻缺血-再灌注和持续缺血引起的心肌损伤,同时能明显减少这二种情况所诱导的心肌细胞凋亡的发生率。Conclusion This study suggested that IP could prevent myocardial injury induced by ischemia-reperfusion and continuous ischemia , and also reduce the rates of myocyte apoptosis in those situations.